Should we introduce compulsory vaccination? Peter M English pp 1-3 Given the overwhelmingly positive benefits of vaccination, it seems odd that
the question of compulsory vaccination should ever arise. Why would anybody
turn down the offer of vaccination? Routine vaccination primarily benefits
the person being vaccinated, and is very safe. The diseases prevented are serious, so refusing vaccination (in the absence of contraindications) does not seem rational. Nevertheless, some people actively refuse to be (or have their children) vaccinated; and others find it too difficult to attend.
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Comment: HPV: the programme begins but the controversy continues Peter M English pp 3-3 Since the first issue of Vaccines in practice, the major events in UK vaccine
policy have been the announcement of the choice of product for the human
papillomavirus (HPV) vaccination programme; and that the programme has commenced. It is too early to be clear about how well the programme is going, but initial reports have been good. This is a credit to the primary care organisations – especially the wonderful
school nurse managers – across the country and to how well they have done, not least in
finding the necessary staff. We have to hope that other crucial work will not consequently be left undone this time around (as I am told it was during the meningitis C campaign).
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Group B streptococcal vaccines: a review Chaam L Klinger pp 4-5 Group B streptococcus (GBS, also known as Streptococcus agalacticae) causes
serious disease in newborn babies. We have known since the 1970s that neonatal sepsis caused by GBS affects about 0.7 per 1,000 live births in the UK, and is fatal in
8% of cases. GBS is also a significant cause of stillbirths and prematurity. More recently, GBS has been seen to cause infections in adults, especially older
people and the chronically ill.
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Biology of immune responses to vaccines in older people Wayne A Mitchell, Ryan C Pink and Richard Aspinall pp 6-8 With increased life expectancy, the growing challenge is how to ensure we
stay healthier for longer. As we age, our immune systems become less able to combat potential pathogens. We need to
adapt our immunisation strategies in order to give best protection to older people. In this review we look at the current vaccination strategies to protect older
people against influenza and
pneumococcal disease.
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ESPID 2008: innovations in vaccination Peter M English pp 9-9 I was delighted to hear, last year, that the 2008 European Society for Paediatric
Infectious Diseases (ESPID) conference would be in Graz, Austria. As my wife comes from South Germany, I was already
well disposed to German-speaking countries; even more so after recent skiing trips to Austria.
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Maintaining the cold chain Roy Fey pp 10-11 ‘The equipment and the people that keep vaccines cold, from the manufacturer to the child [or adult], are together called the cold chain.’ This is the most succinct yet
comprehensive definition of the cold chain that I have found. It correctly stresses the fact that the cold chain relies on people as much as on equipment and delivery systems. Although refrigerators will fail on
occasion, in common with any machine, many reports of ‘fridge failures’ (using this
term to cover all instances of incorrectly stored vaccines) are due to human error.
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